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Increasing your chances for a healthy pregnancy with PGT-A
September 08, 2021
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DR. MICHAEL HARTMAN
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In the past few years, there have been major advancements in the treatment of infertility. Now, for a large majority of people, an infertility diagnosis does not mean the end of your journey to parenthood. Sometimes the treatment is straightforward, but there is good news too, for couples who need a more advanced approach. Our success rates for In Vitro Fertilization (IVF) continue to increase dramatically thanks to innovative treatment enhancements like Preimplantation Genetic Testing for Aneuploidy (PGT-A).

 

IVF involves fertilizing an egg with sperm in a lab to create embryos, which are then transferred into the uterus. Embryos are then “graded” by their appearance which is often used as guidance to determine which ones would provide the best chance for implantation and a healthy pregnancy. While this process does still offer a good success rate, it can be inaccurate – many embryos that look normal fail to implant because the embryo has an abnormal number of chromosomes. PGT-A allows us to determine with much greater accuracy which embryos are the most likely to result in a successful ongoing pregnancy with 46 chromosomes.

Healthy embryos have 23 pairs of chromosomes. Selecting healthy embryos with PGT-A can increase your chances of pregnancy per embryo transfer and decrease your likelihood of miscarriage.

What is PGT-A?

Preimplantation Genetic Testing for Aneuploidy (PGT-A) is a procedure that is used as part of IVF at the embryo stage to helps identify the healthiest embryos. Anyone looking into IVF treatment can benefit from PGT-A, but it can be particularly helpful for patients with eggs who are over 35 or who have experienced pregnancy loss or failed implantation.

What to Expect

PGT-A involves multiple steps performed by different experts and labs. The specialists at Generation Fertility will be your guide throughout the process.

three steps of pgt-a

Once test results are available, your Generation Fertility specialist will discuss the findings with you in detail, including the number of chromosomally normal embryos identified. These embryos will be preferentially selected for transfer.

 

When you’re facing infertility, having all the information at hand about your treatment options can help you feel more confident and in control on your journey to parenthood. If, like many patients, you’re hearing about PGT-A for the first time, you likely will have questions. If IVF is in your future, talk to your Generation Fertility doctor to find out if PGT-A is the right option for you and your family. We’re here to support you and help you thrive.

innovative enhancements genetic testing
About the Author
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DR. MICHAEL HARTMAN M.D., FRCSC, GREI
Dr. Hartman is a reproductive endocrinologist with Generation Fertility. He graduated from the Faculty of Medicine at McMaster University, and became a Fellow of the Royal College of Physicians and Surgeons of Canada in Obstetrics and Gynecology following his residency at Memorial University of Newfoundland. He completed his Fellowship in Gynecologic Reproductive Endocrinology and Infertility at McGill University. Dr. Hartman is the recipient of numerous research awards and recognitions including the Governor General’s Academic Medal and the CFAS Resident Award in 2011.
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