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Treatments & Solutions

We’ll consider the right options to help you improve your chances of conceiving a child, tailored to your specific needs. Discover an overview of these treatments and solutions below.

 

Our team of fertility specialists are experts in providing evidence-based approaches to fertility.

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In Vitro Fertilization (IVF)

For many patients, IVF maximizes the chance of conception and healthy pregnancy. Our team of leading fertility doctors, physicians, and embryologists is highly experienced in safely and effectively providing this advanced approach to In Vitro Fertilization (IVF) treatment in Canada. 

 

While IVF was initially developed to deal with tubal infertility, today, more than half of all IVF procedures are performed for other reasons. Now it is commonly used in response to unexplained infertility and to increase the success rate in cases of sperm-related infertility.

 

Pursuing IVF consultation and treatments can seem overwhelming at times, but our team of experienced fertility doctors are here to walk you through every step of the journey. It is our top priority to give you the best possible chance of reaching your family building goals while supporting you fully throughout your time with us.

Preliminary Stages of IVF

Once you have completed your assessments and reviewed the results, the physician may recommend you proceed with IVF treatment. To support your treatment and provide you with all the information you need to understand the process, preparation steps may include:

 

  • A discussion with your physician to formulate your IVF plan.
  • A meeting with your nurse to review all the information relative to each stage of the treatment with you. You’ll also receive your medications, and learn how to use them and the treatment calendar.
  • A consultation with the urologist if you need epididymal sperm aspiration or testicular sperm extraction. 
  • A blood sample may also be required for genetic testing.
  • For some situations, such as where a known donor or gestational carrier is involved, counselling may be required. We typically encourage counselling in other types of situations too, to support your emotional well-being.
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First Stage:

Ovarian Suppression

This stage is not always required. If the doctor recommends it, it will allow us to replace your natural cycle with an artificial cycle that is controllable through medication. This involves suppressing ovarian function by administering an oral contraceptive and/or a medication that inhibits pituitary gland function. You may experience some menopause-like side effects, such as hot flashes and mood changes.

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Second Stage:

Ovarian Stimulation (superovulation)

This stage is also sometimes called Controlled Ovarian Hyperstimulation (COH). Your ovaries usually produce and release a single egg per cycle. Although this is sufficient for natural conception, conception with IVF usually requires more. Medications are used to stimulate the development of several ovarian follicles so we can help you retrieve more eggs. A transvaginal ultrasound is used to see the number and the diameter of the follicles that have developed.

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Third Stage:

Triggering the Egg Maturation Process

When follicles are large enough and when hormonal levels are adequate, it is time to trigger the ovaries to prepare eggs for maturation and ovulation. The trigger is done by injecting hCG (human chorionic gonadotropin, a pregnancy hormone similar to LH) or a recombinant hormone.

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Fourth Stage:

Egg/Oocyte Retrieval (also referred to as Ovum Pick Up – OPU)

Eggs are retrieved transvaginally under ultrasound guidance. You are given a local anesthetic and a sedative through an i.v. (intravenous) infusion. Having located the mature follicles, the physician will insert a needle, attached to the probe, into each follicle and aspirate the fluid from each of them. If you are interested, you may watch the procedure on the ultrasound monitor. The embryologist analyzes the contents of every follicle under the microscope. Once the procedure is completed, you are told how many eggs were retrieved. On that same day, these eggs will be combined with the sperm, In Vitro, and should fertilize to form embryos.

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Fifth Stage:

Embryo Transfer

Embryo transfer entails placing one or more embryos (usually one) inside the patient’s uterine cavity usually on cycle day 5. It requires a full bladder for better visualization with the abdominal ultrasound probe.

What's Next?

Finally, the most exciting stage of IVF: waiting for a positive pregnancy test. We will perform a blood test 12 days after your transfer to detect the pregnancy hormone hCG. We will call you the same day with the result, and hopefully announce that we see a successful pregnancy.

Accompanying Procedures to IVF

ICSI is performed in severe cases of infertility, when there are not enough spermatozoa, and they are not mobile enough to penetrate the egg. From a sample of the sperm, the embryologist injects into each of the eggs a sperm captured with a glass needle whose tip has a microscopic diameter.

This procedure is performed in case of obstruction of the vas deferens. Most often, this involves collecting spermatozoa which are then analyzed in one of our sperm analysis testing centres. Only the healthiest of them are used for IVF with micro-injection.

This treatment is only performed in vitro fertilization (IVF) with ICSI. This procedure, performed under local anesthesia, involves taking sperm directly from the testicles using a very fine needle. This technique is used when there is a complete absence of spermatozoa in the ejaculate or epididymis, but the testes continue to produce spermatozoa.

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Intrauterine Insemination (IUI)

IUI, or artificial insemination, is a common treatment used in a range of infertility issues. It is considered a less invasive approach, than some other ART (Assisted Reproductive Technology) procedures, because the critical steps necessary for conception must occur as they would without any medical assistance.

If you decide to undergo IUI (artificial insemination), you will first have to undergo a gynecological exam. The physician will insert a thin, flexible catheter through the patient’s cervix into their uterus to deposit a sperm sample. This insertion is painless and the patient can resume their daily activities within minutes. The sperm inserted into the patient’s uterus has been washed in the laboratory to concentrate it. The sperm can come from a chosen partner (artificial insemination with their sperm – AIS) or from a donor (artificial insemination with donor sperm – AID).

  • Infertility problems associated with a low sperm count or with sperm or morphology problems. 
  • Infertility following a cancer treatment (when the patient has planned ahead and has had sperm frozen prior to their treatment).
  • Repeated failures with ovarian stimulation.
  • Unexplained infertility.
  • Major sperm abnormalities, such as a total absence of sperm.
  • Hereditary genetic diseases or infectious diseases that could be transmitted to the other parent.
  • Isoimmunization or other problems.
  • Infertility following a cancer treatment.
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Ovulation Induction

Ovulation induction describes the use of oral or injectable fertility medications (gonadotropins) to stimulate the ovaries to produce mature eggs. The purpose of ovulation induction is to develop and ovulate one or more eggs in someone who normally does not ovulate. Based on your diagnosis, your doctor will prescribe the treatment most appropriate for you.

 

Ovulation induction may be recommended if you:

 

  • Have ovulation problems that have not responded to simpler medications (such as clomiphene citrate).
  • Have unexplained infertility and wish to try ovulation induction in order to increase the number of eggs produced in each cycle. With increased egg production the chance of conception also increases.

 

To be a candidate for ovulation induction you must have a normal uterine cavity, and at least one normal fallopian tube, and the other parent must have a normal sperm count. In the general population, 20% to 25% of healthy, fertile people who are trying to conceive become pregnant each month. In our experience, ovulation induction typically produces pregnancy rates of 10% to 20% per cycle, depending on your age, diagnosis, and duration of infertility. Approximately 15% to 20% of gonadotropin pregnancies will miscarry, similar to the general population.

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Other Treatments

Other treatments our team may recommend include:

 

  • Antibiotics to treat infections
  • Hormones to treat issues such as polycystic ovarian syndrome (PCOS) or pituitary hormone irregularities.
  • Surgical intervention
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Third-Party & Reciprocal Reproduction Solutions

Many of our patients require a sperm donor, a gestational carrier (also referred to as a “surrogate”), embryo donors, or egg donors. We are an experienced fertility clinic in the Toronto area that works seamlessly with third-party programs, while ensuring that health guidelines and regulations are met. We are also experienced in reciprocal IVF which allows more than one partner to be intimately involved in the process.

What to Expect

Everyone’s journey to fertility is unique. Learn what you can expect throughout the fertility treatment journey.

Learn About Treatments & Solutions

Our experienced team of top fertility doctors have shared helpful insights on elements of your well-being that impact your IVF Treatment. Check out the following quick reads to learn more.

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    Inclusion of all gender & sexually diverse people is an important value of Generation Fertility. We are continuously striving to create an environment of compassionate belonging where all of the 2SLGBTQIA+ community are supported, valued and respected.

    Generation Fertility is situated in the Territory and Treaty 13 lands of the Mississaugas of the Credit First Nation, the traditional territories of the Wendat, Haudeno-saunee and the Anishinaabe peoples, and treaty land of the Williams Treaties First Nations and other Indigenous people.

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